CSI Salud Integral
Por qué es importante estimular la célula fibroblastos para mejorar el aspecto de la piel
Blog|May 21, 2026

Why is it important to stimulate fibroblast cells to improve the appearance of the skin?

Everyone has dermal fibroblasts, a type of cell that contributes to the formation of connective tissue, a fibrous cellular material that supports and connects other tissues and organs in the body. These cells are excellent at secreting collagen and play an important role in wound healing. Medically, fibroblasts are obtained from a person through a skin biopsy and can be cultured in the laboratory for use in genetic studies. In aesthetic terms, stimulating fibroblast cells significantly improves the appearance of the skin, rejuvenating the face by enhancing its structure (increasing tone and hydration and reducing wrinkles ).

Why is stimulating dermal fibroblasts so effective?

Basically, because it’s been shown that collagen loss in the body begins between the ages of 18 and 29 , but after age 40, the body loses around 1% of its collagen per year. If fibroblast cells are stimulated through treatments, this near-complete disappearance of collagen can be prevented.

Why choose an aesthetic medicine treatment instead of simply buying a cosmetic product?

For an active ingredient to stimulate fibroblast activity and proliferation, it needs to penetrate the epidermis and reach the dermis. This is very difficult to achieve with cosmetics alone because the skin is designed to act as a barrier against foreign substances. Therefore, the effect of many cosmetic actives may be insufficient or nonexistent in stimulating fibroblasts. However, a good superficial peel with quality exfoliants (abrasive or chemical substances) and the use of vitamin A derivatives are always beneficial. Given this situation, at our Comprehensive Health Clinic, we always recommend our specialized Radiesse treatment, an injectable biostimulator (dermal filler) with a non-surgical facelift effect.

How does Radiesse work to rejuvenate the face?

  • It stimulates the body’s fibroblast cells to produce collagen in a localized way, which increases the firmness and elasticity of the skin in specific parts of the body.
  • It has an immediate smoothing effect that eliminates wrinkles, facial lines, and unwanted expressions. It also helps to combat creases caused by acne or scars.

The best part is that Radiesse delivers immediate results in just a 20-minute session, but reaches optimal results 3 months after the treatment, which then last for 2 years or more. Contact us if you have any questions about how this innovative procedure could help you eliminate wrinkles and look younger and more beautiful. We’d be happy to assist you!

Stimulate fibroblast cells to improve the appearance of the skin